Variability in the management and outcomes of extremely preterm births across five European countries: a population-based cohort study
Lucy K Smith, Beatrice Blondel, Patrick Van Reempts, Elizabeth S Draper, Bradley N Manktelow, Henrique Barros, Marina Cuttini, Jennifer Zeitlin, for the EPICE Research Group
Arch Dis Child Fetal Neonatal Ed. (2017)
As a result of improved antenatal and neonatal care, survival has increased for infants born at the limits of viability, however not without risk of severe morbidities. Counselling parents and making decisions about treatments for these infants is difficult, as survival rates vary widely. The aim was to explore international variations in the management and survival of extremely low gestational age and birthweight births in the EPICE regions of Belgium, France, Italy, Portugal and the UK.
Association of Short Antenatal Corticosteroid Administration-to-Birth Intervals With Survival and Morbidity Among Very Preterm Infants: Results From the EPICE Cohort
Mikael Norman, Aurelie Piedvache, Klaus Børch, Lene Drasbek Huusom, Anna-Karin Edstedt Bonamy, Elizabeth A. Howell, Pierre-Henri Jarreau, Rolf F. Maier, Ole Pryds, Liis Toome, Heili Varendi, Tom Weber, Emilija Wilson, Arno Van Heijst, Marina Cuttini, Jan Mazela, Henrique Barros, Patrick Van Reempts, Elizabeth S. Draper, Jennifer Zeitlin, for the Effective Perinatal Intensive Care in Europe (EPICE) Research Group
JAMA Pediatr. (2017)
Antenatal corticosteroids (ANS) are administered to pregnant women at risk of delivery before 34 weeks of gestation, in order to reduce morbidity and mortality in their infants. The administration-to-birth intervals of ANS varies, and it is not known how close to delivery ANS administration is efficient. The aim was to explore the association between the time from first ANS injection to delivery and survival and morbidity among 4594 singleton very preterm infants in all 19 of the EPICE regions.